« RETURN TO DIRECTORY

Shengmin Sang

Research Professor

North Carolina Agricultural and Technical State University
College
College of Ag & Environ Sciences

Department
Cntr of Excellence-Post Harvest Tec

Contact
Nutrition Research Institute Building, North Carolina Research Campus 4222
Education
B.S.Chemical Education / Shandong Normal University
Ph.D.Chemistry / Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Bio

Dr. Shengmin Sang obtained his Ph.D. degree as a natural product chemist from Shanghai Institute of Material Medicine, Chinese Academy of Sciences in 1999. He is currently an Associate Professor and Lead Scientist for Functional Foods and Human Health of North Carolina Agricultural and Technical State Univesity at North Carolina Research Campus in Kannapolis. He is also a full-faculty member in the UNC Linebergar Comprehensive Cancer Center at UNC Chapel Hill and an adjunct faculty in the Department of Food, Bioprocessing and Nutritional Sciences at North Carolina State University.

Research Interests

Dr. Shengmin Sang’s lab has interest to purify and identify bioactive components from functional foods and herbal medicine and to further study their bioavailability, biotransformation, and preventive effects on cancer and metabolic syndrome using in vitro and in vivo models. His main areas of research interest are: • Purifying and identifying bioactive components from herbal medicine and functional foods; • Standardization and quality control of herbal medicine and functional foods; • Studying the bioavailability and biotransformation of bioactive food components in cells, animals and humans, and the impact of microbiota on the bioavailability and efficacy of polyphenols; • Studying the preventive effects of dietary polyphenols on the development of diabetic complications focusing on the trapping of reactive dicarbonyl compounds and the formation of Advanced Glycation End Products (AGEs) using in vitro and animal models; • Developing new agents to prevent cancer from dietary sources using in vitro and animal models. • Using metabolomic approach to study dietary exposure markers.

Recent Publications

  • Christian Jobin, Christina Ohland, Shengmin Sang, Shuwei Zhang, Yantao Zhao (2019). (Microbiota facilitates the formation of the aminated metabolite of green tea polyphenol (-)-epigallocatechin-3-gallate which trap deleterious reactive endogenous metabolites). 131, pp. 332--344 ). Free Radical Biology and Medicine.
  • Karine Ferri-Lagneau, Jamil Haider, TinChung Leung, Shengmin Sang (2019). (Rescue of hematopoietic stem/progenitor cells formation in plcg1 zebrafish mutant). (1) 9, pp. 244 ). Scientific reports.
  • Shengmin Sang, Hunter Snooks, Yingdong Zhu (2018). (Complexity of Advanced Glycation End Products in Foods: Where Are We Now?). (6) 66, pp. 1325-1329 ). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.
  • Shengmin Sang (2018). (Novel theaflavin-type chlorogenic acid derivatives identified in black tea. ). 66, pp. 3402-3407 ). J. Agric. Food Chem. .
  • Lishuang Lv, Shengmin Sang, Weixin Wang, Shuwei Zhang (2018). (A new method to prepare and redefine black tea thearubigins). 1563, pp. 82--88 ). Journal of Chromatography A.
  • Emmanuel Idehen, Shengmin Sang, Yao Tang, Wenbin Wu, Junli Yang (2018). (Avenanthramide aglycones and glucosides in oat bran: Chemical profile, levels in commercial oat products, and cytotoxicity to human colon cancer cells). (30) 66, pp. 8005--8014 ). Journal of agricultural and food chemistry.
  • Shengmin Sang (2018). (Biomarkers of Whole Grain Intake). (40) 66, pp. 10347--10352 ). Journal of agricultural and food chemistry.
  • Shengmin Sang, Hunter Snooks, Yingdong Zhu (2018). (Complexity of Advanced Glycation End Products in Foods: Where Are We Now?). (6) 66, pp. 1325--1329 ). Journal of agricultural and food chemistry.
  • Hengqing Cui, Yu Hou, Yongling Lu, Lishuang Lv, Shengmin Sang, Fei Tao, Tiesong Zheng (2018). (Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress). 265, pp. 227--232 ). Food chemistry.
  • Chi-Tang Ho, Junqing Huang, Shiming Li, Qing Meng, Shengmin Sang, Xiaochun Wan, Chia-Cheng Wei (2018). (Importance of the nucleophilic property of tea polyphenols). ). Journal of agricultural and food chemistry.
  • Junsheng Fu, Shengmin Sang, Dominique Soroka, Yingdong Zhu (2018). (Induction of Apoptosis and Cell-Cycle Arrest in Human Colon-Cancer Cells by Whole-Grain Alkylresorcinols via Activation of the p53 Pathway). (45) 66, pp. 11935--11942 ). Journal of Agricultural and Food Chemistry.
  • Chi-Tang Ho, Wei-Lun Hung, Shengmin Sang, Xiaochun Wan, Siyu Wang, Yu Wang (2018). (Quantification of ascorbyl adducts of epigallocatechin gallate and gallocatechin gallate in bottled tea beverages). 261, pp. 246--252 ). Food chemistry.
  • Hengqing Cui, Yu Hou, Yongling Lu, Lishuang Lv, Shengmin Sang, Zhengjun Xie, Tiesong Zheng (2018). (Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts). 269, pp. 396--403 ). Food chemistry.
  • Emmanuel Idehen, Shengmin Sang, Yao Tang (2017). (Bioactive phytochemicals in barley). (1) 25, pp. 148-161 ). Journal of Food and Drug Analysis.
  • Shengmin Sang, Fang Wang, Pei Wang, Yantao Zhao, Yingdong Zhu (2017). (Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer). 7, pp. 40119 ). Scientific Reports.
  • Guimei Liu, Yongling Lu, Lishuang Lv, Shengmin Sang, Qiuqin Xia, Tiesong Zheng (2017). (Influence of Quercetin and Its Methylglyoxal Adducts on the Formation of α-Dicarbonyl Compounds in a Lysine/Glucose Model System). (10) 65, pp. 2233-2239 ). Journal of Agricultural and Food Chemistry.
  • Mary Grace, Mary Lila, Yin Qiang, Shengmin Sang (2017). (One-step isolation of carnosic acid and carnosol from rosemary by centrifugal partition chromatography). (5) 40, pp. 1057-1062 ). Journal of Separation Science.
  • Yi Chu, Shengmin Sang (2017). (Whole grain oats, more than just a fiber: Role of unique phytochemicals). pp. 1600715 ). Molecular Nutrition & Food Research.
  • Muhammed Ahmedna, Muhammed Rashid, Chethan Sampath, Shengmin Sang (2017). (Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway). 226, pp. 79-88 ). Food Chemistry.
  • Mohamed Ahmedna, Sampath Chethan, Muhammed Rashid, Shengmin Sang (2017). (Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via Nrf2 pathway in mice with high fat diet-induced obesity). 87, pp. 73-81 ). Biomedicine & Pharmacotherapy.