« RETURN TO DIRECTORY

Shengmin Sang

Research Professor

North Carolina Agricultural and Technical State University
Contact
Nutrition Research Institute Building, North Carolina Research Campus 4222
Education
Ph.D.Chemistry / Shanghai Institute of Materia Medica, Chinese Academy of Sciences
B.S.Chemical Education / Shandong Normal University

Bio

Dr. Shengmin Sang obtained his Ph.D. degree as a natural product chemist from Shanghai Institute of Material Medicine, Chinese Academy of Sciences in 1999. He is currently an Associate Professor and Lead Scientist for Functional Foods and Human Health of North Carolina Agricultural and Technical State Univesity at North Carolina Research Campus in Kannapolis. He is also a full-faculty member in the UNC Linebergar Comprehensive Cancer Center at UNC Chapel Hill and an adjunct faculty in the Department of Food, Bioprocessing and Nutritional Sciences at North Carolina State University.

Research Interests

Dr. Shengmin Sang’s lab has interest to purify and identify bioactive components from functional foods and herbal medicine and to further study their bioavailability, biotransformation, and preventive effects on cancer and metabolic syndrome using in vitro and in vivo models. His main areas of research interest are: • Purifying and identifying bioactive components from herbal medicine and functional foods; • Standardization and quality control of herbal medicine and functional foods; • Studying the bioavailability and biotransformation of bioactive food components in cells, animals and humans, and the impact of microbiota on the bioavailability and efficacy of polyphenols; • Studying the preventive effects of dietary polyphenols on the development of diabetic complications focusing on the trapping of reactive dicarbonyl compounds and the formation of Advanced Glycation End Products (AGEs) using in vitro and animal models; • Developing new agents to prevent cancer from dietary sources using in vitro and animal models. • Using metabolomic approach to study dietary exposure markers.

Recent Publications

  • Shuwei Zhang, Yantao Zhao, Christina Ohland, Christian Jobin, Shengmin Sang, Shuwei Zhang, Shengmin Sang (2019). (Microbiota facilitates the formation of the aminated metabolite of green tea polyphenol (-)-epigallocatechin-3-gallate which trap deleterious reactive endogenous metabolites). 131, pp. 332--344 ). Free Radical Biology and Medicine.
  • Karine Ferri-Lagneau, Jamil Haider, Shengmin Sang, TinChung Leung, Karine Ferri-Lagneau, Shengmin Sang (2019). (Rescue of hematopoietic stem/progenitor cells formation in plcg1 zebrafish mutant). (1) 9, pp. 244 ). Scientific reports.
  • Shengmin Sang, Shengmin Sang (2018). (Biomarkers of Whole Grain Intake). (40) 66, pp. 10347--10352 ). Journal of agricultural and food chemistry.
  • Qing Meng, Shiming Li, Junqing Huang, Chia-Cheng Wei, Xiaochun Wan, Shengmin Sang, Chi-Tang Ho, Qing Meng, Shengmin Sang (2018). (Importance of the nucleophilic property of tea polyphenols). ). Journal of agricultural and food chemistry.
  • Wenbin Wu, Yao Tang, Junli Yang, Emmanuel Idehen, Shengmin Sang, Wenbin Wu, Shengmin Sang (2018). (Avenanthramide aglycones and glucosides in oat bran: Chemical profile, levels in commercial oat products, and cytotoxicity to human colon cancer cells). (30) 66, pp. 8005--8014 ). Journal of agricultural and food chemistry.
  • Yingdong Zhu, Hunter Snooks, Shengmin Sang, Shengmin Sang, Yingdong Zhu (2018). (Complexity of Advanced Glycation End Products in Foods: Where Are We Now?). (6) 66, pp. 1325--1329 ). Journal of agricultural and food chemistry.
  • Wei-Lun Hung, Siyu Wang, Shengmin Sang, Xiaochun Wan, Yu Wang, Chi-Tang Ho, Wei-Lun Hung, Shengmin Sang (2018). (Quantification of ascorbyl adducts of epigallocatechin gallate and gallocatechin gallate in bottled tea beverages). 261, pp. 246--252 ). Food chemistry.
  • Weixin Wang, Shuwei Zhang, Lishuang Lv, Shengmin Sang, Weixin Wang, Shengmin Sang (2018). (A new method to prepare and redefine black tea thearubigins). 1563, pp. 82--88 ). Journal of Chromatography A.
  • Hengqing Cui, Fei Tao, Yu Hou, Yongling Lu, Tiesong Zheng, Shengmin Sang, Lishuang Lv, Hengqing Cui, Shengmin Sang (2018). (Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress). 265, pp. 227--232 ). Food chemistry.
  • Yu Hou, Zhengjun Xie, Hengqing Cui, Yongling Lu, Tiesong Zheng, Shengmin Sang, Lishuang Lv, Yu Hou, Shengmin Sang (2018). (Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts). 269, pp. 396--403 ). Food chemistry.
  • Junsheng Fu, Dominique Soroka, Yingdong Zhu, Shengmin Sang, Junsheng Fu, Shengmin Sang (2018). (Induction of Apoptosis and Cell-Cycle Arrest in Human Colon-Cancer Cells by Whole-Grain Alkylresorcinols via Activation of the p53 Pathway). (45) 66, pp. 11935--11942 ). Journal of Agricultural and Food Chemistry.
  • Yingdong Zhu, Hunter Snooks, Shengmin Sang, Yingdong Zhu, Shengmin Sang (2018). (Complexity of Advanced Glycation End Products in Foods: Where Are We Now?). (6) 66, pp. 1325-1329 ). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.
  • Shengmin Sang, Shengmin Sang (2018). (Novel theaflavin-type chlorogenic acid derivatives identified in black tea. ). 66, pp. 3402-3407 ). J. Agric. Food Chem. .
  • Sampath Chethan, Muhammed Rashid, Shengmin Sang, Mohamed Ahmedna, Sampath Chethan, Shengmin Sang (2017). (Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via Nrf2 pathway in mice with high fat diet-induced obesity). 87, pp. 73-81 ). Biomedicine & Pharmacotherapy.
  • Pei Wang, Yantao Zhao, Yingdong Zhu, Shengmin Sang, Pei Wang, Yantao Zhao, Shengmin Sang (2017). (Glucuronidation and its impact on the bioactivity of [6]-shogaol). (9) 61, ). MOLECULAR NUTRITION & FOOD RESEARCH.
  • Yingdong Zhu, Fang Wang, Yantao Zhao, Pei Wang, Shengmin Sang, Yingdong Zhu, Shengmin Sang (2017). (Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer). 7, pp. 40119 ). Scientific Reports.
  • Mary Grace, Yin Qiang, Shengmin Sang, Mary Lila, Mary Grace, Shengmin Sang (2017). (One-step isolation of carnosic acid and carnosol from rosemary by centrifugal partition chromatography). (5) 40, pp. 1057-1062 ). Journal of Separation Science.
  • Yingdong Zhu, Fang Wang, Yantao Zhao, Pei Wang, Shengmin Sang, Yingdong Zhu, Pei Wang, Shengmin Sang (2017). (Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer). 7, ). SCIENTIFIC REPORTS.
  • Pei Wang, Junli Yang, Aaron Yerke, Shengmin Sang, Shengmin Sang, Pei Wang, Junli Yang (2017). (Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake). (7) 61, ). MOLECULAR NUTRITION & FOOD RESEARCH.
  • Emmanuel Idehen, Yao Tang, Shengmin Sang, Emmanuel Idehen, Shengmin Sang (2017). (Bioactive phytochemicals in barley). (1) 25, pp. 148-161 ). Journal of Food and Drug Analysis.