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Jian Han

Associate Professor

North Carolina Agricultural and Technical State University
Contact
Barnes Hall 206
Education
Ph.D.Nutrition / Pennsylvania State University
M.S.Nutritional Sciences / University of Hawaii at Manoa
OtherZoology / Nankai University
OtherEcology and Environmental Biology / Nankai University
Ph.D.Nutrition / Pennsylvania State University
M.S.Nutritional Sciences / University of Hawaii at Manoa
OtherZoology / Nankai University
OtherEcology and Environmental Biology / Nankai University

Research Interests

My research activities focus on nutrition modulation of complex diseases, with an emphasis on iron metabolism. Iron is an essential nutrient for all living cells. It is involved in DNA synthesis, energy production, and enzymatic reactions. It also interacts with other nutrients and modifies the expression of many genes. Both my graduate and post-graduate work emphasized iron storage and transfer protein expression in either normal or diseased conditions. Two major projects are 1) the investigation of iron-induced oxidative stress and neurotoxicity in obesity; 2) the effect of dietary iron manipulation on insulin sensitivity in obese mice.

My research activities focus on nutrition modulation of complex diseases, with an emphasis on iron metabolism. Iron is an essential nutrient for all living cells. It is involved in DNA synthesis, energy production, and enzymatic reactions. It also interacts with other nutrients and modifies the expression of many genes. Both my graduate and post-graduate work emphasized iron storage and transfer protein expression in either normal or diseased conditions. Two major projects are 1) the investigation of iron-induced oxidative stress and neurotoxicity in obesity; 2) the effect of dietary iron manipulation on insulin sensitivity in obese mice.

Recent Publications

  • Kalan, M Kalan (2019). (Quality of Life and Stigma among People Living with HIV/AIDS in Iran.). (2019) 11, pp. 287—298 ). HIV/AIDS - Research and Palliative Care.
  • Mohammad Kalan, Hassan Sis, Gregory Goins, Scott Harrison, Vinaya Kelkar, Mohammad Jafarabadi, Jian Han, Jian Han, Gregory Goins, Scott Harrison, Vinaya Kelkar, Mohammad Kalan (2018). (The Identification of Risk Factors Associated with Patient and Healthcare System Delays in the Treatment of Tuberculosis in Tabriz, Iran). (1) 18, pp. 174 ). BMC Public Health.
  • Mohammad Kalan, Hassan Sis, Gregory Goins, Scott Harrison, Vinaya Kelkar, Mohammad Jafarabadi, Jian Han, Jian Han, Gregory Goins, Scott Harrison, Vinaya Kelkar, Mohammad Kalan (2018). (The Identification of Risk Factors Associated with Patient and Healthcare System Delays in the Treatment of Tuberculosis in Tabriz, Iran). (1) 18, pp. 174 ). BMC Public Health.
  • Lumei Liu, Aria Byrd, Justin Plummer, Keith Erikson, Scott Harrison, Jian Han, Jian Han, Lumei Liu, Scott Harrison (2016). (The Effects of Dietary Fat and Iron Interaction on Brain Regional Iron Contents and Stereotypical Behaviors in Male C57BL/6J Mice). 3, pp. 20 ). Frontiers in Nutrition.
  • Lumei Liu, Aria Byrd, Justin Plummer, Keith Erikson, Scott Harrison, Jian Han, Jian Han, Lumei Liu, Scott Harrison (2016). (The Effects of Dietary Fat and Iron Interaction on Brain Regional Iron Contents and Stereotypical Behaviors in Male C57BL/6J Mice). 3, pp. 20 ). Frontiers in Nutrition.
  • Zhijian Xie, Scott Harrison, Suzy Torti, Frank Torti, Jian Han, Scott Harrison, Suzy Torti, Zhijian Xie, Jian Han (2013). (Application of circuit simulation method for differential modeling of TIM-2 iron uptake and metabolism in mouse kidney cells. ). (136) 4, pp. 1-9 ). Frontiers in Physiology.
  • Zhijian Xie, Scott Harrison, Suzy Torti, Frank Torti, Jian Han, Scott Harrison, Suzy Torti, Zhijian Xie, Jian Han (2013). (Application of circuit simulation method for differential modeling of TIM-2 iron uptake and metabolism in mouse kidney cells. ). (136) 4, pp. 1-9 ). Frontiers in Physiology.
  • Jian Han, W Seaman, D Xiu, W Wang, F Torti, S Torti, Jian Han, W Seaman (2011). (Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells). (8) 6, ). Plosone.
  • G Bailey, Jian Han, Donela Wright, Joseph Graves, G Bailey, Jian Han, Joseph Graves, Donela Wright (2011). (Religously expressed fatalism and the perceived need for science and scientific process to empower agency). (3) 2, pp. 55-58 ). The international journal of science in society.
  • G Bailey, Jian Han, Donela Wright, Joseph Graves, G Bailey, Jian Han, Joseph Graves, Donela Wright (2011). (Religously expressed fatalism and the perceived need for science and scientific process to empower agency). (3) 2, pp. 55-58 ). The international journal of science in society.
  • Jian Han, W Seaman, D Xiu, W Wang, F Torti, S Torti, Jian Han, W Seaman (2011). (Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells). (8) 6, ). Plosone.
  • Jian Han, AJ Thompson-Lowrey, A Reiss, V Mayorov, H Jia, V Bousse, NJ Newman, MD Brown, Jian Han, AJ Thompson-Lowrey (2006). (OPA1 mutations and mitochondrial DNA haplotypes in autosomal dominant optic atrophy). (4) 8, pp. 217-25 ). Genetic Medicine.
  • Jian Han, AJ Thompson-Lowrey, A Reiss, V Mayorov, H Jia, V Bousse, NJ Newman, MD Brown, Jian Han, AJ Thompson-Lowrey (2006). (OPA1 mutations and mitochondrial DNA haplotypes in autosomal dominant optic atrophy). (4) 8, pp. 217-25 ). Genetic Medicine.
  • Jian Han, JR Day, JR Connor, JL Beard, Jian Han, JR Day (2002). (H and L ferritin subunit mRNA expression in control vs iron-deficient rat brain). (132) pp. 2769-74 ). Journal of Nutrition.
  • Jian Han, JR Day, JR Connor, JL Beard, Jian Han, JR Day (2002). (H and L ferritin subunit mRNA expression in control vs iron-deficient rat brain). (132) pp. 2769-74 ). Journal of Nutrition.
  • Jian Han, J Han, MA Dunn, Jian Han, J Han (2000). (Effect of dietary aluminum on tissue non-heme ion and ferritin levels in the chick). (142) pp. 97-109 ). Toxicology.
  • Jian Han, J Han, MA Dunn, Jian Han, J Han (2000). (Effect of dietary aluminum on tissue non-heme ion and ferritin levels in the chick). (142) pp. 97-109 ). Toxicology.
  • Jian Han, JR Day, JR Connor, JL Beard, Jian Han, JR Day (2000). (Iron deficiency alters H- and L- ferritin expression in rat brain). (46) pp. 517-528 ). Cellular and Molecular Biology.
  • Jian Han, JR Day, JR Connor, JL Beard, Jian Han, JR Day (2000). (Iron deficiency alters H- and L- ferritin expression in rat brain). (46) pp. 517-528 ). Cellular and Molecular Biology.
  • Joseph Graves, A EwunkemA, Misty Thomas, Jian Han, K Rhinehardt , S Boyd, R Edmondson, Liesl Jeffers-Francis, Scott Harrison, , , A EwunkemA, Jian Han, Joseph Graves, Misty Thomas, Liesl Jeffers-Francis, Scott Harrison (Experimental Evolution of Metal Resistance in Bacteria). (Evolution in Action—Past, Present, and Future) ). Springer 2 International Publishing, AG.