Chih Kuan Tung

Assistant Professor

North Carolina Agricultural and Technical State University
Marteena Hall 301
B.S.Physics / National Taiwan University
Ph.D.Physics / Princeton University


Chih-kuan grew up in Taiwan, received his BS from National Taiwan University and PhD from Princeton University, both in physics. He then took up postdoc positions at Hong Kong University of Science and Technology, University of Pittsburgh, and Cornell University, before joining A&T faculty in 2006. Since Princeton, his research has focused on using micro/nanofabricated devices for biological applications. At Cornell, Chih-kuan noticed that sperm exhibit interesting emergent behaviors, which became his current research focus. Trained as a physicist, he is interested in the fundamental physics in living systems.

Research Interests

Biological physics, microfluidic in vitro models for biological systems, collective dynamics and phase separation of cells. Soft and active matters. Influence of physical environment on mammalian sperm motility.

Recent Publications

  • Chungwei Lin, Tim Marks, Milutin Pajovic, Shinji Watanabe, Chih Kuan Tung, Chungwei Lin, Chih Kuan Tung (2018). (Model parameter learning using Kullback-Leibler divergence). 491, pp. 549 ). Physica A.
  • Chih Kuan Tung, Chungwei Lin, Benedict Harvey, Alyssa Fiore, Florencia Ardon, Mingming Wu, Susan Suarez, Chih Kuan Tung, Chungwei Lin (2017). (Fluid viscoelasticity promotes collective swimming of sperm). 7, pp. 3152 ). Scientific Reports.
  • Wei Song, Chih Kuan Tung, Yen-Chun Lu, Yehudah Pardo, Mingming Wu, Moumita Das, Der-I Kao, Shuibing Chen, Minglin Ma, Wei Song, Chih Kuan Tung (2016). (Dynamic self-organization of microwell-aggregated cellular mixtures). 12, pp. 5739 ). Soft Matter.
  • Florencia Ardon, Ross Markello, Lian Hu, Zarah Deutsch, Chih Kuan Tung, Walaa Alshafie, Thomas Yaros, Robert Gilbert, Mingming Wu, Susan Suarez, Florencia Ardon, Chih Kuan Tung (2016). (Dynamics of bull sperm interaction with epithelium differ between oviductal isthmus and ampulla). (4) 95, pp. 90 ). Biology of Reproduction.
  • Chih Kuan Tung, Florencia Ardon, Anubhab Roy, Donald Koch, Susan Suarez, Mingming Wu, Florencia Ardon, Chih Kuan Tung (2015). (Emergence of upstream swimming via a hydrodynamic transition). (10) 114, pp. 108102 ). Physical review letters.
  • Yu Huang, Chih Kuan Tung, Anqi Zheng, Beum Kim, Mingming Wu, Yu Huang, Chih Kuan Tung (2015). (Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model). (11) 7, pp. 1402 ). Integrative Biology.
  • Beum Kim, Lubna Richter, Nicholas Hatter, Chih Kuan Tung, Beth Ahner, Mingming Wu, Beum Kim, Chih Kuan Tung (2015). (An array microhabitat system for high throughput studies of microalgal growth under controlled nutrient gradients). (18) 15, pp. 3687 ). Lab on a Chip.
  • Chih Kuan Tung, Lian Hu, Alyssa Fiore, Florencia Ardon, Dillon Hickman, Robert Gilbert, Susan Suarez, Mingming Wu, Lian Hu, Chih Kuan Tung (2015). (Microgrooves and fluid flows provide preferential passageways for sperm over pathogen Tritrichomonas foetus). (17) 112, pp. 5431 ). Proceedings of the National Academy of Sciences.
  • Chih Kuan Tung, Florencia Ardon, Alyssa Fiore, Susan Suarez, Mingming Wu, Chih Kuan Tung, Florencia Ardon (2014). (Cooperative roles of biological flow and surface topography in guiding sperm migration revealed by a microfluidic model). (7) 14, pp. 1348 ). Lab on a chip.
  • Chih Kuan Tung, Oleh Krupa, Elif Apaydin, Jr-Jiun Liou, Anthony Diaz-Santana, Beum Kim, Mingming Wu, Chih Kuan Tung, Oleh Krupa (2013). (A contact line pinning based microfluidic platform for modelling physiological flows). (19) 13, pp. 3876 ). Lab on a chip.
  • Bret Davis, Junhan Pan, Chih Kuan Tung, Robert Austin, Robert Riehn, Bret Davis, Chih Kuan Tung (2013). (Sensing DNA with alternating currents using a nanogap sensor embedded in a nanochannel device). (01) 3, pp. 1340007 ). Nano LIFE.
  • Hanna Salman, Naama Brenner, Chih Kuan Tung, Noa Elyahu, Elad Stolovicki, Lindsay Moore, Albert Libchaber, Erez Braun, Hanna Salman, Chih Kuan Tung (2012). (Universal protein fluctuations in populations of microorganisms). (23) 108, pp. 238105 ). Physical review letters.
  • Qiucen Zhang, Guillaume Lambert, David Liao, Hyunsung Kim, Kristelle Robin, Chih Kuan Tung, Nader Pourmand, Robert Austin, Qiucen Zhang, Chih Kuan Tung (2011). (Acceleration of emergence of bacterial antibiotic resistance in connected microenvironments). (6050) 333, pp. 1764–1767 ). Science.
  • Robert Austin, Chih Kuan Tung, Guillaume Lambert, David Liao, Xiuqing Gong, Chih Kuan Tung, Robert Austin (2010). (An introduction to micro-ecology patches). (3) 39, pp. 1049–1059 ). Chemical Society Reviews.
  • Shuang Lim, Robert Riehn, Chih Kuan Tung, William Ryu, Rui Zhuo, Joanna Dalland, Robert Austin, Shuang Lim, Chih Kuan Tung (2009). (Upconverting nanophosphors for bioimaging). (40) 20, pp. 405701 ). Nanotechnology.
  • Chih Kuan Tung, Robert Riehn, Robert Austin, Robert Riehn, Chih Kuan Tung (2009). (Complementary metal oxide semiconductor compatible fabrication and characterization of parylene-C covered nanofluidic channels with integrated nanoelectrodes). (3) 3, pp. 031101 ). Biomicrofluidics.
  • Robert Riehn, Walter Reisner, Jonas Tegenfeldt, Yan Wang, Chih Kuan Tung, Shuang-Fang Lim, Edward Cox, James Sturm, Keith Morton, Steven Chou, others, Robert Riehn, Chih Kuan Tung (2007). (Nanochannels for Genomic DNA Analysis: The Long and the Short of It). pp. 151–186 ). Integrated Biochips for DNA Analysis.
  • Chih-Yuan Hsiao, Yen Sun, Wei-Liang Chen, Chih Kuan Tung, Wen Lo, Jiunn-Wen Su, Sung-Jan Lin, Shiou-Hwa Jee, Gwo-Jen Jan, Chen-Yuan Dong, Chih Kuan Tung, Chih-Yuan Hsiao (2006). (Effects of different immersion media in multiphoton imaging of the epithelium and dermis of human skin). (12) 69, pp. 992–997 ). Microscopy research and technique.
  • Shuang Lim, Robert Riehn, William Ryu, Nora Khanarian, Chih Kuan Tung, David Tank, Robert Austin, Chih Kuan Tung, Shuang Lim (2006). (In vivo and scanning electron microscopy imaging of upconverting nanophosphors in Caenorhabditis elegans). (2) 6, pp. 169–174 ). Nano Letters.
  • Chih Kuan Tung, Yen Sun, Wen Lo, Sung-Jan Lin, Shiou-Hwa Jee, Chen-Yuan Dong, Chih Kuan Tung, Yen Sun (2004). (Effects of objective numerical apertures on achievable imaging depths in multiphoton microscopy). (6) 65, pp. 308–314 ). Microscopy research and technique.