Chih Kuan Tung

Assistant Professor

North Carolina Agricultural and Technical State University
College of Science and Technology


Marteena Hall 301
B.S.Physics / National Taiwan University
Ph.D.Physics / Princeton University


Chih-kuan grew up in Taiwan, received his BS from National Taiwan University and PhD from Princeton University, both in physics. He then took up postdoc positions at Hong Kong University of Science and Technology, University of Pittsburgh, and Cornell University, before joining A&T faculty in 2006. Since Princeton, his research has focused on using micro/nanofabricated devices for biological applications. At Cornell, Chih-kuan noticed that sperm exhibit interesting emergent behaviors, which became his current research focus. Trained as a physicist, he is interested in the fundamental physics in living systems.

Research Interests

Biological physics, microfluidic in vitro models for biological systems, collective dynamics and phase separation of cells. Soft and active matters. Influence of physical environment on mammalian sperm motility.

Recent Publications

  • Chungwei Lin, Tim Marks, Milutin Pajovic, Chih Kuan Tung, Shinji Watanabe (2018). (Model parameter learning using Kullback-Leibler divergence). 491, pp. 549 ). Physica A.
  • Florencia Ardon, Alyssa Fiore, Benedict Harvey, Chungwei Lin, Susan Suarez, Chih Kuan Tung, Mingming Wu (2017). (Fluid viscoelasticity promotes collective swimming of sperm). 7, pp. 3152 ). Scientific Reports.
  • Shuibing Chen, Moumita Das, Der-I Kao, Yen-Chun Lu, Minglin Ma, Yehudah Pardo, Wei Song, Chih Kuan Tung, Mingming Wu (2016). (Dynamic self-organization of microwell-aggregated cellular mixtures). 12, pp. 5739 ). Soft Matter.
  • Walaa Alshafie, Florencia Ardon, Zarah Deutsch, Robert Gilbert, Lian Hu, Ross Markello, Susan Suarez, Chih Kuan Tung, Mingming Wu, Thomas Yaros (2016). (Dynamics of bull sperm interaction with epithelium differ between oviductal isthmus and ampulla). (4) 95, pp. 90 ). Biology of Reproduction.
  • Beth Ahner, Nicholas Hatter, Beum Kim, Lubna Richter, Chih Kuan Tung, Mingming Wu (2015). (An array microhabitat system for high throughput studies of microalgal growth under controlled nutrient gradients). (18) 15, pp. 3687 ). Lab on a Chip.
  • Florencia Ardon, Donald Koch, Anubhab Roy, Susan Suarez, Chih Kuan Tung, Mingming Wu (2015). (Emergence of upstream swimming via a hydrodynamic transition). (10) 114, pp. 108102 ). Physical review letters.
  • Yu Huang, Beum Kim, Chih Kuan Tung, Mingming Wu, Anqi Zheng (2015). (Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model). (11) 7, pp. 1402 ). Integrative Biology.
  • Florencia Ardon, Alyssa Fiore, Robert Gilbert, Dillon Hickman, Lian Hu, Susan Suarez, Chih Kuan Tung, Mingming Wu (2015). (Microgrooves and fluid flows provide preferential passageways for sperm over pathogen Tritrichomonas foetus). (17) 112, pp. 5431 ). Proceedings of the National Academy of Sciences.
  • Florencia Ardon, Alyssa Fiore, Susan Suarez, Chih Kuan Tung, Mingming Wu (2014). (Cooperative roles of biological flow and surface topography in guiding sperm migration revealed by a microfluidic model). (7) 14, pp. 1348 ). Lab on a chip.
  • Elif Apaydin, Anthony Diaz-Santana, Beum Kim, Oleh Krupa, Jr-Jiun Liou, Chih Kuan Tung, Mingming Wu (2013). (A contact line pinning based microfluidic platform for modelling physiological flows). (19) 13, pp. 3876 ). Lab on a chip.
  • Robert Austin, Bret Davis, Junhan Pan, Robert Riehn, Chih Kuan Tung (2013). (Sensing DNA with alternating currents using a nanogap sensor embedded in a nanochannel device). (01) 3, pp. 1340007 ). Nano LIFE.
  • Erez Braun, Naama Brenner, Noa Elyahu, Albert Libchaber, Lindsay Moore, Hanna Salman, Elad Stolovicki, Chih Kuan Tung (2012). (Universal protein fluctuations in populations of microorganisms). (23) 108, pp. 238105 ). Physical review letters.
  • Robert Austin, Hyunsung Kim, Guillaume Lambert, David Liao, Nader Pourmand, Kristelle Robin, Chih Kuan Tung, Qiucen Zhang (2011). (Acceleration of emergence of bacterial antibiotic resistance in connected microenvironments). (6050) 333, pp. 1764–1767 ). Science.
  • Robert Austin, Xiuqing Gong, Guillaume Lambert, David Liao, Chih Kuan Tung (2010). (An introduction to micro-ecology patches). (3) 39, pp. 1049–1059 ). Chemical Society Reviews.
  • Robert Austin, Robert Riehn, Chih Kuan Tung (2009). (Complementary metal oxide semiconductor compatible fabrication and characterization of parylene-C covered nanofluidic channels with integrated nanoelectrodes). (3) 3, pp. 031101 ). Biomicrofluidics.
  • Robert Austin, Joanna Dalland, Shuang Lim, Robert Riehn, William Ryu, Chih Kuan Tung, Rui Zhuo (2009). (Upconverting nanophosphors for bioimaging). (40) 20, pp. 405701 ). Nanotechnology.
  • Steven Chou, Edward Cox, Shuang-Fang Lim, Keith Morton, Walter Reisner, Robert Riehn, James Sturm, Jonas Tegenfeldt, Chih Kuan Tung, Yan Wang (2007). (Nanochannels for Genomic DNA Analysis: The Long and the Short of It). pp. 151–186 ). Integrated Biochips for DNA Analysis.
  • Wei-Liang Chen, Chen-Yuan Dong, Chih-Yuan Hsiao, Gwo-Jen Jan, Shiou-Hwa Jee, Sung-Jan Lin, Wen Lo, Jiunn-Wen Su, Yen Sun, Chih Kuan Tung (2006). (Effects of different immersion media in multiphoton imaging of the epithelium and dermis of human skin). (12) 69, pp. 992–997 ). Microscopy research and technique.
  • Robert Austin, Nora Khanarian, Shuang Lim, Robert Riehn, William Ryu, David Tank, Chih Kuan Tung (2006). (In vivo and scanning electron microscopy imaging of upconverting nanophosphors in Caenorhabditis elegans). (2) 6, pp. 169–174 ). Nano Letters.
  • Chen-Yuan Dong, Shiou-Hwa Jee, Sung-Jan Lin, Wen Lo, Yen Sun, Chih Kuan Tung (2004). (Effects of objective numerical apertures on achievable imaging depths in multiphoton microscopy). (6) 65, pp. 308–314 ). Microscopy research and technique.