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Patrick McPhail Martin

Interim Associate Dean

Patrick McPhail Martin
Contact
Smith Hall 2002
Education
Ph.D.Cell Biology / University of Virginia
B.S.Biology / Virginia Union University

Bio

The primary research interest focus of my group is to investigate the regulation of malignant brain, breast and prostate tumor formation, metastatic progression as well as developing drugs that effectively inhibit the oncogenic characteristics of tumors. Another research interest is examining the underlying cellular principles of cancers that are more aggressive in African-Americans. Specifically, our research interests are examining why African-American women are disproportionately affected by breast cancers and African American men are diagnosed with prostate cancers that are highly metastatic and resistant to known therapeutic regimens. R

Research Interests

brain and breast tumor research, cancer health disparities, research training education

Recent Publications

  • Antonio Baines, Patrick Martin, Checo Rorie, Patrick Martin, Checo Rorie, Antonio Baines (2016). (Current and Emerging Targeting Strategies for Treatment of Pancreatic Cancer). In Kevin Pruitt, (Molecular and Cellular Changes in the Cancer Cell) 144, pp. 277-320 ).
  • S Sandhaus, R Taylor, T Edwards, A Huddleston, Y Wooten, R Venkatraman, R Weber, A González-Sarrías, Patrick Martin, P Cagle, Y Tse-Dinh, S Beebe, N Seeram, A Holder, S Sandhaus, Patrick Martin (2016). (A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα.). 64, pp. 45-49 ). Inorganic chemistry communications.
  • Jennie Williams, Lesley Lewis-Alleyne, Melinda Solomon, Long Nguyen, Robert Johnson, Jennifer Vital , Ping Ji, John Durrant, Camille Cooper, Patrice Cagle, Patrick Martin, Don VanDerveer, William Jarrett, Alvin Holder, Jennie Williams, Patrick Martin (2016). (An in vitro study on the effect of synthesized tin(IV) complexes on glioblastoma, colorectal and skin cancer cell lines.). (1) 1, pp. 7-15 ).
  • Patrick Martin, Patrick Martin (2014). (contributing author). pp. 880-885 ). Molecular Medicine Reports.
  • E Mahdavian, M Marshall, Patrick Martin, P Cagle, B Salvatore, Q Quick, E Mahdavian, Patrick Martin (2014). (Caspase-dependent signaling underlies glioblastoma cell death in response to the fungal metabolite, fusarochromanone.). (3) 34, pp. 880-5 ). International journal of molecular medicine.
  • I González, Patrick Martin, C Burdsal, J Sloan, S Mager, T Harris, A Sutherland, I González, Patrick Martin (2012). (Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo.). (2) 361, pp. 286-300 ). Developmental biology.
  • Patrick Martin, S Aeder, C Chrestensen, T Sturgill, I Hussaini, Patrick Martin, S Aeder (2007). (Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta.). (3) 26, pp. 407-14 ). Oncogene.
  • R Uht, S Amos, Patrick Martin, A Riggan, I Hussaini, R Uht, Patrick Martin (2007). (The protein kinase C-eta isoform induces proliferation in glioblastoma cell lines through an ERK/Elk-1 pathway.). (20) 26, pp. 2885-93 ). Oncogene.
  • S Amos, Patrick Martin, G Polar, S Parsons, I Hussaini, S Amos, Patrick Martin (2005). (Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells.). (9) 280, pp. 7729-38 ). The Journal of biological chemistry.
  • Patrick Martin, I Hussaini, I Hussaini, Patrick Martin (2005). (PKC eta as a therapeutic target in glioblastoma multiforme.). (2) 9, pp. 299-313 ). Expert opinion on therapeutic targets.
  • S Aeder, Patrick Martin, J Soh, I Hussaini, S Aeder, Patrick Martin (2004). (PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways.). (56) 23, pp. 9062-9 ). Oncogene.
  • Patrick Martin, A Sutherland, L Van Winkle, Patrick Martin, A Sutherland (2003). (Amino acid transport regulates blastocyst implantation.). (4) 69, pp. 1101-8 ). Biology of reproduction.
  • Patrick Martin, A Sutherland, Patrick Martin, A Sutherland (2001). (Exogenous amino acids regulate trophectoderm differentiation in the mouse blastocyst through an mTOR-dependent pathway.). (1) 240, pp. 182-93 ). Developmental biology.