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Ming Dong

Associate Professor

Ming Dong
Google Scholar

College
College of Science and Technology

Department
Chemistry

Contact
New Science Building 333
P: 336-285-2234
Education
Ph.D.Chemistry and Biochemistry / University of Delaware
M.S.Biochemical Engineering / Hebei University of Technology
B.S.Biochemical Engineering / Hebei University of Technology

Research Interests

Research in the lab is focused on protein structure and function. We apply biochemistry, X-ray crystallography and computational modeling to obtain a deep understanding of the mechanisms underlying redox regulated phosphorylation of metabolic enzymes.

External URL

https://sites.google.com/view/mdong/

Recent Publications

  • Ming Dong (2021). (A Minireview on Temperature Dependent Protein Conformational Sampling.). (4) 40, pp. 545-553. The protein journal.
  • Kristen Rhinehardt, Ming Dong (2021). (Computational analysis of protein conformational heterogeneity.). pp. 1-6. Journal of biomolecular structure & dynamics.
  • Jeannette Delva-Wiley, Israt Jahan, Robert Newman, Lifeng Zhang, Ming Dong (2021). (Computational analysis of the binding mechanism of GenX and HSA. ). ACS Omega.
  • Jeannette Delva-Wiley, Israt Jahan, Robert Newman, Lifeng Zhang, Ming Dong (2021). (Computational Analysis of the Binding Mechanism of GenX and HSA). 6, pp. 29166-29170. ACS Omega.
  • M Shafei, T Forshaw, J Davis, A Flemban, D Qualtrough, S Dean, C Perks, Ming Dong, Robert Newman, M Conway (2020). (BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.). (21) 11, pp. 1971-1987. Oncotarget.
  • M Harris, M El Hindy, M Usmari-Moraes, F Hudd, M Shafei, Ming Dong, M Hezwani, P Clark, M House, T Forshaw, P Kehoe, M Conway (2020). (BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease.). 152, pp. 755-766. Free radical biology & medicine.
  • Darius Herbert, Synphane Gibbs, Alexys Riddick, M Conway, Ming Dong (2020). (Crystal structure of an oxidized mutant of human mitochondrial branched-chain aminotransferase). (1) 76, Acta Crystallographica Section F: Structural Biology Communications.
  • Dongyang Deng, Lifeng Zhang, Ming Dong, Raymond Samuel, Andrea Ofori-Boadu, Mehdi Lamssali (2020). (Radioactive waste: A review). Water Environment Research.
  • Dongyang Deng, Lifeng Zhang, Ming Dong, R Samuel, Andrea Ofori-Boadu, M Lamssali (2020). (Radioactive waste: A review.). (10) 92, pp. 1818-1825. Water environment research : a research publication of the Water Environment Federation.
  • Ming Dong, T Gonzalez, M Klems, L Steinberg, W Chen, E Papoutsakis, B Bahnson (2017). (In vitro methanol production from methyl coenzyme M using the Methanosarcina barkeri MtaABC protein complex.). Biotechnology progress.
  • S Schaefer, Ming Dong, R Rubenstein, W Wilkie, B Bahnson, C Thorpe, S Rozovsky (2013). ((77)Se enrichment of proteins expands the biological NMR toolbox.). (2) 425, pp. 222-31. Journal of molecular biology.
  • Stephanie Schaefer, Ming Dong, Brian Bahnson, Colin Thorpe, Sharon Rozovsky (2013). (Conversion of the Sulfhydryl Oxidase Augmenter of Liver Regeneration into a Selenoprotein). (2) 104, pp. 396a. Biophysical Journal.
  • Z Nagel, C Meadows, Ming Dong, B Bahnson, J Klinman (2012). (Active site hydrophobic residues impact hydrogen tunneling differently in a thermophilic alcohol dehydrogenase at optimal versus nonoptimal temperatures.). (20) 51, pp. 4147-56. Biochemistry.
  • Z Nagel, Ming Dong, B Bahnson, J Klinman (2011). (Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors.). (26) 108, pp. 10520-5. Proceedings of the National Academy of Sciences of the United States of America.
  • V Daithankar, S Schaefer, Ming Dong, B Bahnson, C Thorpe (2010). (Structure of the human sulfhydryl oxidase augmenter of liver regeneration and characterization of a human mutation causing an autosomal recessive myopathy .). (31) 49, pp. 6737-45. Biochemistry.
  • Ming Dong, Shuting Qi (2006). (Conjugated linoleic acid production by fermentation). (4) 2, pp. 1128. International Journal of Food Engineering.
  • Kristen Rhinehardt, Ming Dong (Computational analysis of protein conformational heterogeneity). pp. 1-6. Journal of Biomolecular Structure and Dynamics.
  • Jeannette Delva-Wiley, Israt Jahan, Robert Newman, Lifeng Zhang, Ming Dong (Computational Analysis of the Binding Mechanism of GenX and HSA). (0) 0, pp. null. ACS Omega.
  • Stephanie Schaefer, Ming Dong, Brian Bahnson, Colin Thorpe, Sharon Rozovsky (Protein Folding & Stability I).