Robert H. Newman

TitleAssociate Professor

DepartmentBiology

Phone336-285-2189

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Emailrhnewman@ncat.edu

OfficeBarnes Hall
Room: 105

1601 East Market Street
Greensboro, NC 27411

Robert H. Newman

Education

Ph D: Biochemistry and Molecular Biology, Johns Hopkins University, 2007

BA: Biology and Biochemistry, McDaniel College, 1999


Research Interests

We are interested in understanding the regulation of phosphorylation-dependent signaling pathways. Research is organized around two central questions: 1) which cellular proteins are phosphorylated by a given kinase and 2) how are specific kinases and phosphatases—and ultimately the signaling networks of which they are a part—regulated within the cellular environment? To answer these questions, we take a two-pronged approach based on 1) systems-level analysis of kinase-substrate relationships and the biochemical factors underlying kinase substrate selection and 2) the development and application of genetically-targetable FRET-based biosensors.


Recent Publications

Cao, Lei  Sedighi, Rashin  Boston, Ava  Premadasa, Lakmini  Pinder, Jamilla  Crawford, George  Jegede, Olugbemiga  Harrison, Scott  Newman, Robert  Ongeri, Elimelda  (2018).  Undiagnosed kidney injury in uninsured and underinsured diabetic African American men and putative role of meprin metalloproteases in diabetic nephropathy.   International Journal of Nephrology.

Ismail, H  Newman, Robert  Kc, Dukka  (2016).  RF-Hydroxysite: a random forest based predictor for hydroxylation sites..  (8,  12,  pp. 2427-35).  Molecular bioSystems.

Ewunkem, Akamu  Parson, Carl  Muganda, Perpetua  Newman, Robert  (2015).  A Low-Cost Method for Tracking the Induction of Apoptosis using FRET-based Activity Sensors in Suspension Cells.  In PM Muganda,  Apoptosis   Methods in Toxicology/Humana Press.