Perpetua Mubweri Muganda

TitleProfessor

DepartmentBiology

Phone336-285-2190

Emailpmmugand@ncat.edu

OfficeHines Hall
Room: 317

1601 East Market Street
Greensboro, NC 27411

Perpetua Mubweri Muganda

Education

Ph D: Biochemistry, Indiana University School of Medicine, 1983

MS: Biochemistry, Howard University, 1978

BS: Biology, Lock Haven State College, 1976


Research Interests

tumor virology and systems biology, molecular carcinogenesis, cellular and molecular mechanisms of toxicity, role of p53 in carcinogenesis and toxicity, apoptotic signaling and mechanism.


Recent Publications

Muganda,  Perpetua  ( 2016).  An Overview of Apoptosis Methods in Toxicological Research: Recent Updates .  In Perpetua Muganda  ( 1st/2016 Edition,  pp. 1-12).   Apoptosis Methods in Toxicology.

Muganda,  Perpetua  ( 2016).  Apoptosis Methods in Toxicology.  In Perpetua Muganda, Ph.D.,  Methods in Pharmacology and Toxicology  ( 1/2016 Edition,  pp. 244).   Springer Science and Business media, LLC.

Ewunkem,  Akamu  Muganda,  Perpetua  ( 2016).  Determining the Extent of Toxicant-Induced Apoptosis Using Concurrent Phased Apoptosis Assays.  In Perpetua Muganda  ( 1st/2016 Edition,  pp. 31-47).   Apoptosis Methods in Toxicology.

Ewunkem,  Akamu  Parson,  Carl  Muganda,  Perpetua  Newman,  Robert  ( 2015).  A Low-Cost Method for Tracking the Induction of Apoptosis using FRET-based Activity Sensors in Suspension Cells.  In PM Muganda,  Apoptosis    Methods in Toxicology/Humana Press.

Muganda,  Perpetua  ( 2011).  Nanomedicine-Based Synthetic Biology.  ( 1,  1,  pp. 1000102e).   Journal of Nanomedicine & Biotherapeutic Discovery.

Muganda,  Perpetua  ( 2009).  Mechanisms of Diepoxybutane-Induced p53 Regulation in Human Cells.  ( 23 (6),  pp. 373-386).   Journal of Biochemical and Molecular Toxicology.

Muganda,  Perpetua  ( 2007).  Diepoxybutane Activates the Mitochondrial Apoptic Pathway and Mediates Apoptosis in Human Lymphoblasts Through Oxidative Stress.  Toxicology In Virtro  ( 21,  pp. 1429-1441).   North Carolina A&T State University.

Muganda,  Perpetua  ( 2007).  Genetic Engineering of Site Specific Mutations Targeting the NF-kB Binding Site Within the Human p53 Promoter.  SMART Findings: Undergraduate STEM Research Journal  ( 1(1),  pp. 13-19).   Southern University at Baton Rouge.

Muganda,  Perpetua  ( 2005).  Accute Exposure to Human Lung Cells to 1, 3-Butadiene Diepoxide Results in G1 and G2 Cell Cycle Arrest.  Env. Mol. Mutagenesis  ( 45 (4),  pp. 354-364).   North Carolina A&T State University.

Muganda,  Perpetua  ( 2004).  Diepoxybutane Induses Caspase and p53 Mediated Apoptosis in Human Lymphocytes.  Toxicology and Applied Pharmacology  ( 195 (2),  pp. 154-165).   North Carolina A&T State University.

Muganda,  Perpetua  ( 1998).  The Human Cytomegalovirus IE286 Kilodalton Protein Elevates p53 Levels and Transactivates the p53 Promoter in Human Fibroblasts.  Cellular and Molecular Biology  ( 44(2),  pp. 321-331).   North Carolina A&T State University.

Muganda,  Perpetua  ( 1995).  Identification of Casein Kinase Activity Found Elevated in Human Cytomegalovirus Transformed Cells.  Biochem. Biophys. Res. Comm.  ( 207(2),  pp. 740-746).   University of Texas at El Paso.

Muganda,  Perpetua  ( 1994).  Human Cytomegalovirus Elevates Levels of the Cellular Protein p53 in Infected Fibroblasts.  Virology  ( 68 (12) ,  pp. 8028-8034).   Department of Biological Science.

Muganda-Ojiaku,  Perpetua  ( 1987).  Alteration of Protein Phosphorylation Patterns in Human Cytomegalovirus-Induced Morphological Transformation.  Cancer Biochemistry and Biophysics  ( 9(2),  pp. 179-189).   North Carolina A&T State University.

Muganda-Ojiaku,  Perpetua  ( 1986).  Extraction and Quantative Precipitation of Nuclear Ribonuleoprotein Particles.  Preparative Biochemistry  ( 1-20,  16(1),  ).   North Carolina A&T State University.

Muganda,  Perpetua  ( 1978).  Cyclic Nucleotide Metabolism in Solid Tumor Tissues. .  Advances in Experimental Medicine and Biology   ( 92,  pp. 489-516).   Plenum Press, N.Y..