Elimelda Ongeri

TitleAssociate Professor

DepartmentBiology

Phone336-285-2182

Fax336-334-7105

Emaileongeri@ncat.edu

OfficeBarnes Hall
Room: 215

1601 East Market Street
Greensboro, NC 27411

Elimelda Ongeri

Education

Other: Ovarian Gene Regulation, Pennsylvania State University, 2005

Ph D: Animal Sciences, Purdue University, 2001

MS: Basic Medical Sciences, Purdue University, 1999

MS: Animal Physiology, University of Nairobi, 1994

BS: Animal Production, Egerton University, 1990


Research Interests

Research in the Ongeri lab focuses on understanding the cellular and molecular mechanisms underlying acute and chronic kidney disease. We work with in vitro cell culture systems, mouse models, and samples from human patients. Of specific interest to my group is determining the role of meprin metalloproteases in the progression of kidney injury. We utilize surgical procedures for induction of acute kidney injury in the ischemia/reperfusion mouse model. For diabetic kidney disease (DKD), we are interested in understanding the basis for health disparities and in identifying biomarkers associated with susceptibility genes for DKD. Such biomarkers


Recent Publications

Cao,  Lei  Sedighi,  Rashin  Boston,  Ava  Premadasa,  Lakmini  Pinder,  Jamilla  Crawford,  George  Jegede,  Olugbemiga  Harrison,  Scott  Newman,  Robert  Ongeri,  Elimelda  ( 2018).  Undiagnosed kidney injury in uninsured and underinsured diabetic African American men and putative role of meprin metalloproteases in diabetic nephropathy.    International Journal of Nephrology.

Bylander,  J  Ahmed,  F  Conley,  S  Mwiza,  J-M  Ongeri,  E  ( 2017).  Meprin Metalloproteases Deficiency Associated with Higher Mortality rates and More Severe Diabetic Kidney Injury in Mice with STZ-induced type 1 diabetes..  No  ( https://doi.org/10.1155/2017/9035038,  2017 (2017),  pp. 11).   Journal of Diabetes Research.

Martin,  Barry  Conley,  Sabena  Harris,  Regine  Stanley,  Corshe  Niyitegeka,  Jean-Marie  Ongeri,  Elimelda  ( 2016).  Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin beta.    International Journal of Nephrology.

Kumar,  Nitin  Nakagawa,  P  Janic,  B  Romero,  C  Worou,  M  Monu,  S  Peterson ,  E  Shaw ,  J  Valeriote,  F  Ongeri,  Elimelda  Niyitegeka ,  Jean-Marie  Rhaleb ,  N  Carretero,  O  ( 2016).  The Anti-Inflammatory Peptide Ac-SDKP is Released from Thymosin β4 by Renal Meprin alpha and Prolyl Oligopeptidase.  No  ( 1,  308,  pp. F56-68).   American Journal of Physiology - Renal.

Niyitegeka,  J-M  Bastidas,  A  Newman,  R  Taylor,  S  Ongeri,  E  ( 2015).  Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of protein kinase A: Significance in acute and chronic kidney injury.  no  ( 308,  pp. F56 - F68).   American Journal of Physiology - Renal.

Niyitegeka,  Jean-Marie  Newman,  Robert  Ongeri,  Elimelda  ( 2015).  Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of Protein Kinase A: Significance in acute and chronic kidney injury.  No  ( 308,  pp. F56-F68).   American Journal of Physiology - Renal.