Antoinette M. Maldonado-Devincci

TitleAssistant Professor




OfficeNew Science Building
Room: 228

1601 East Market Street
Greensboro, NC 27411

Antoinette M. Maldonado-Devincci


Ph D: Psychobiology, University of South Florida , 2011

MA: Psychology, University of South Florida , 2007

BA: Psychology, University of South Florida, 2004

Research Interests

My current research focuses on the role of alcohol's effects modulation of particular systems in the brain, namely GABAergic neurosteroids. My current research has two overall goals. The first goal to is understand the development of neuroactive steroids during adolescence and how drug exposure during this developmental period would contribute to abnormal brain development and drug-seeking and drug-taking behavior. The second aim is to understand how alcohol dependence changes brain neurocircuitry and how these changes can be reversed by potential therapeutic intervention.

Recent Publications

Bell, Richard  Hauser, Sheketha  Liang, Tiebing  Sari, Youssef  Maldonado-Devincci, Antoinette  Rodd, Zachary  (2017).  Rat Animal Models for Screening Medications to Treat Alcohol Abuse and Dependence.  (122,  pp. 201-243).  Neuropharmacology.

Beattie, M  Maldonado-Devincci, Antoinette  Porcu, P  O'Buckley, T  Daunais, J  Grant, K  Morrow, A  (2017).  Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) in the amygdala of the cynomolgus monkey.  (2,  22,  pp. 318-330).  Addiction Biology.

Hasirci, A.  Maldonado-Devincci, Antoinette  Beattie, Matthew  O'Buckley, Todd  Morrow, A.  (2017).  Cellular GABAergic neuroactive steroid (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) immunostaining levels are increased in the ventral tegmental area of the human Alcohol Use Disorder patient: A postmortem study.  (2,  41,  pp. 299-311).  Alcoholism, Clinical and Experimental Research.

Beattie, Matthew  Maldonado-Devincci, Antoniette  Cook, Jason  Morrow, A.  (2016).  The Effects of Acute and Chronic Ethanol Exposure on GABAergic Neuroactive Steroid Immunohistochemistry: Relationship to Ethanol Drinking.  In Victor R. Preedy,  Neuropathology of Drug Addictions and Substance Misuse Volume 1: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids and Opioids   Academic Press.

Maldonado-Devincci, Antoniette  Kampov-Polevoi, Alexander  McKinley, Raechel  Morrow, Danielle  O’Buckley, Todd  Morrow, A.  (2016).  Chronic intermittent ethanol exposure alters stress effects on (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) immunolabeling of amygdala neurons in C57BL/6J mice.  (10,  pp. 12).  Frontiers in Cellular Neuroscience.

Pleil, K  Lowery-Gionta, E  Crowley, N  Li , C  Marcinkiewcz, C  Rose, J  McCall, N  Maldonado-Devincci, A  Morrow, A  Jones, S  Kash, T  (2015).  Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala.  (99,  pp. 735-49).  Neuropharmacology.

Maldonado-Devincci, Antoniette  Cook, J  O'Buckley, T  Morrow, D  McKinley, R  Lopez, M  Becker, H  Morrow, A  (2014).  Chronic intermittent ethanol exposure and withdrawal alters (3α,5α)-3-hydroxy-pregnan-20-one immunostaining in cortical and limbic brain regions of C57BL/6J mice.  (10,  38,  pp. 2561-71).  Alcoholism, Clinical and Experimental Research.

Maldonado-Devincci, Antoniette  Beattie, M  Morrow, D  McKinley, R  Cook, J  O'Buckley, T  Morrow, A  (2014).  Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice.  (17,  231,  pp. 3281-92).  Psychopharmacology.

Cook, J  Nelli, S  Neighbors, M  Morrow, D  O'Buckley, T  Maldonado-Devincci, Antoniette  Morrow, A  (2014).  Ethanol alters local cellular levels of (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP) independent of the adrenals in subcortical brain regions.  (8,  39,  pp. 1978-87).  Neuropsychopharmacology .

Cook, J  Werner, D  Maldonado-Devincci, Antoniette  Leonard, M  Fisher, K  O'Buckley, T  Porcu, P  McCown, T  Besheer, J  Hodge, C  Morrow, A  (2014).  Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.  (17,  34,  pp. 5824-34).  The Journal of Neuroscience : the official journal of the Society for Neuroscience.