 Margaret I. Kanipes
Associate Professor of Chemistry
Department of Chemistry
Greensboro, NC 27411
Phone: (336) 433-6708
Fax: (336) 334-7124
mikanipe@ncat.edu
Education
Duke University, Durham, NC - Postdoctoral Fellow Biochemistry - 1997-2001
Carnegie Mellon University, Pittsburgh, PA - Ph.D. Biological Sciences - 1990-1997
N.C. A & T State University, Greensboro, NC - B.S. Chemistry - 1986-1990
Research Interests
Lipid enzymology, bacterial genetics and genomics.
Professional Organizations
American Society for Microbiology
The American Association for the Advancement of Science
Phi kappa Phi National Honor Society
Current Research Projects
- Analysis of Campylobacter coli Lipooligosaccharide Core Diversity
The major goals of this project are characterization of the LOS biosynthetic loci from C. coli Penner serostrains and the analysis of C. coli LOS core diversity among clinical isolates.
NIH Academic Research Enhancement Award (AREA R15), $210,000
- Development of a Genotyping Scheme for Identifying Strains of Campylobacter jejuni
This project involves the development of a genotyping scheme for identifying strains of the food-borne bacterial pathogen, Campylobacter jejuni.
Dept. of Army: HBCU/MI Research and Instrumentation Grant, $290,460
Dept. of Army: HBCU/MI Instrumentation, $5,000
- Analysis of mutants involved in the assembly of lipo-oligosaccharide in Campylobacter jejuni
Selected Most Recent Publications
Kanipes M.I., Papp-Szabo E.,Guerry, P. and Monteiro M. A. 2006. Mutation of waaC, encoding heptosyltransferase I in Campylobacter jejuni 81-176, affects the structure of both lipooligosaccharide and capsular carbohydrate. J. Bacteriol. 188: 3273-3279.
Kanjilal-Kolar S, Basu S.S., Kanipes M.I., Guan Z., Garrett T.A., Raetz C. R. 2006. Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases. J. Biol. Chem. 281: 12865-12878.
Papp-Szabo E., Kanipes M.I., Guerry P., Monteiro M.A. 2005. Cell-surface alpha-glucan in Campylobacter jejuni 81-176. Carbohydr. Res. 13: 2218-2221.
Kanipes M.I., Holder L.C., Corcoran A.T., Moran A.P., and Guerry P. 2004. A deep rough mutant of Campylobacter jejuni 81-176 is non-invasive for intestinal epithelial cells. Infect. Immun. 72: 2452-2455.
Most Recent Presentations
Kanipes M.I., Rockabrand D., Guerry, P. Akelaitis A., Li J., Monteiro M.A. 2006. Characterization of a Campylobacter jejuni 81-176 Two Domain Glycosyltransferase Mutant Involved in Lipooligosaccharide Biosynthesis. 106th General Meeting of the American Society for Microbiology. Orlando, Florida.
Kanipes M.I., Holder L.C., and Guerry P. 2005. Biological and Structural Characterization of the Campylobacter jejuni 81-176 LgtF Mutant. 105th General Meeting of the American Society for Microbiology. Atlanta, Georgia.
Kanipes M.I., Holder L.C., and Guerry P. 2004. Isolation and Characterization of the Heptose Deficient Campylobacter jejuni 81-176 WaaC mutant. 104th General Meeting of the American Society for Microbiology. New Orleans, LA.
Kanipes M.I. Holder L.C., and Guerry P. 2003. Isolation and Characterization of the Campylobacter jejuni 81-176 WaaF. 103rd General Meeting of the American Society for Microbiology. Washington, DC.
Collaborations
Naval Medical Research Center-Silver Spring, Maryland
US Naval Medical Research Unit-Cairo, Egypt
Inspiration/Motivation
I was inspired to become a researcher in the academy by my graduate advisor at a time when I did not see many women represented in the sciences. I have been very fortunate to have the opportunity to return to my alma mater, North Carolina Agricultural and Technical State University to teach and train young people to become responsible scientists.
Vision
My vision is to continue to develop my research laboratory in the area of bacterial genomics and to increase it to accommodate the training and mentoring of undergraduate students, MS and PhD candidates and postdoctoral fellows.
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