 Jenora T. Waterman, Ph.D.
Assistant Professor
North Carolina A&T State University
Department of Animal Sciences
1601 East Market Street
Greensboro, NC 27411
Education and Training
- B.S., Biology, Bennett College for Women, Greensboro, NC
- M.S., Biology, North Carolina A&T State University, Greensboro, NC
- Ph.D., Functional Genomics, North Carolina State University, Raleigh, NC
- Post-doctoral Training, Cell Biology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC
Professional Affiliations
- American Society for Cell Biology
- American Thoracic Society
- Society of Nematologists
- American Dairy Science Association
Research Interests
The Comparative Genomic Sciences Lab (CGSL, Waterman Lab) is interested in elucidating the extent of environmental and genomic influences on the pathophysiology of respiratory diseases. We employ comparative genomics and reverse translational medicine approaches to study NF-κB-mediated inflammation, oxidant stress and hyperreactivity in the airways of laboratory and farm animals, and humans. Model systems include fully differentiated primary airway epithelial cells and cell lines (from mice, pigs, cows and humans) maintained in a unique air-liquid interface culturing system. Cells grown in this manner are essentially identical to cells in the body with regard to structure and function.
Current Research Projects
- Comparative Genomic and Proteomic Analysis of Reactive Dust-mediated Oxidant Stress in Swine Airway Epithelial Cells
- Comparative Genomics of the Impact of Confinement versus Pasture-based Rearing of Hogs on Airway Epithelial Cell Function in Pigs and Humans
- Genomics/Proteomics of Airway Epithelial Cell Differentiation In Vitro
Collaborators
- Dr. Mulumebet Worku, Associate Professor and Biotechnologist
Department of Animal Sciences, North Carolina A&T State University
- Dr. Sang Hyon Oh, Adjunct Assistant Professor
Department of Animal Sciences, North Carolina A&T State University
- Dr. Kenneth B. Adler, Professor of Cell Biology
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University
Teaching Responsibilities
- ANSC 637 Environmental Toxicology
- ANSC 782 Cellular Pathobiology
- LASC 461 Physiology of Domestic Animals
- LASC 636 Principles of Toxicology
Recent Presentations
- Waterman, J.T. and Adler, K.B. 2009. Differential Effects of Albuterol and Formoterol Isomers on NF-B Activation in Human Airway Epithelial Cells. American Thoracic Society International Conference. San Diego, CA.
- Waterman, J.T., Jones, J.N. and Adler, K.B. 2008. Albuterol-induced Oxidant Stress in Primary Cultures of Normal Human Bronchial Epithelial Cells. American Thoracic Society International Conference. Toronto, Ontario.
- Waterman, J.T., Park, J.-A., Crews, A.L. and Adler, K.B. 2007. The (S)-enantiomer of albuterol activates expression of iNOS via activation of NF-B in primary cultures of normal human bronchial epithelial cells. American Thoracic Society International Conference. San Francisco, CA.
Selected Publications
- Waterman, J. T. and Adler, K.B. 2008. Oxidant stress and airway epithelial function. In: Free Radical Effects on Membranes. Ed. Matalon, S. Academic Press. New York. Pp. 243-55.
- Waterman, J.T., Jones, J.N. and Adler, K.B. 2008. Albuterol-induced oxidant stress in primary cultures of normal human bronchial epithelial cells. American Journal of Respiratory and Critical Care Medicine 177, 469A.
- Waterman, J.T., Park, J.A., Crews, A.L., and Adler, K.B. 2007. The (S)-enantiomer of albuterol activates expression of iNOS via activation of NF-B in primary cultures of normal human bronchial epithelial cells. American Journal of Respiratory and Critical Care Medicine 175, 178A.
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