Shengmin Sang

TitleAssociate Professor

DepartmentFamily and Consumer Sciences

Phone704-250-5710

Fax704-250-5709

Emailssang@ncat.edu

OfficeNutrition Research Institute Building, North Carolina Research Campus
Room: 4222

1601 East Market Street
Greensboro, NC 27411

Shengmin Sang

Education

Ph D: Medicinal Chemistry, Shanghai Institute of Material Medica, Chinese Academy of Science, 1999

BS: Orgamic Chemistry/Phytochemistry, Shandong Normal University, 1994


Research Interests

Dr. Shengmin Sang’s lab has interest to purify and identify bioactive components from functional foods and herbal medicine and to further study their bioavailability, biotransformation, and preventive effects on cancer and metabolic syndrome using in vitro and in vivo models. His main areas of research interest are: • Purifying and identifying bioactive components from herbal medicine and functional foods; • Standardization and quality control of herbal medicine and functional foods; • Studying the bioavailability and biotransformation of bioactive food components in cells, animals and humans, and the impact of microbiota on the bioavailability and efficacy of polyphenols; • Studying the preventive effects of dietary polyphenols on the development of diabetic complications focusing on the trapping of reactive dicarbonyl compounds and the formation of Advanced Glycation End Products (AGEs) using in vitro and animal models; • Developing new agents to prevent cancer from dietary sources using in vitro and animal models. • Using metabolomic approach to study dietary exposure markers.


Recent Publications

Liu, Guimei  Xia, Qiuqin  Lu, Yongling  Zheng, Tiesong  Sang, Shengmin  Lv, Lishuang  (2017).  Influence of Quercetin and Its Methylglyoxal Adducts on the Formation of α-Dicarbonyl Compounds in a Lysine/Glucose Model System.  (10,  65,  pp. 2233-2239).  Journal of Agricultural and Food Chemistry.

Grace, Mary  Qiang, Yin  Sang, Shengmin  Lila, Mary  (2017).  One-step isolation of carnosic acid and carnosol from rosemary by centrifugal partition chromatography.  (5,  40,  pp. 1057-1062).  Journal of Separation Science.

Sampath, Chethan  Rashid,  Muhammed   Sang, Shengmin  Ahmedna, Muhammed  (2017).  Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway.  (226,  pp. 79-88).  Food Chemistry.

Chethan, Sampath  Rashid, Muhammed  Sang, Shengmin  Ahmedna, Mohamed  (2017).  Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via Nrf2 pathway in mice with high fat diet-induced obesity.  (87,  pp. 73-81).  Biomedicine & Pharmacotherapy.

Sang, Shengmin  Chu, Yi  (2017).  Whole grain oats, more than just a fiber: Role of unique phytochemicals.   Molecular Nutrition & Food Research.

Idehen, Emmanuel  Tang, Yao  Sang, Shengmin  (2017).  Bioactive phytochemicals in barley.  (1,  25,  pp. 148-161).  Journal of Food and Drug Analysis.

Zhu, Yingdong  Wang, Fang  Zhao, Yantao  Wang, Pei  Sang, Shengmin  (2017).  Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer.  (7,  pp. 40119).  Scientific Reports.

Sampath, Chethan  Sang, Shengmin  Ahmedna, Mohamed  (2016).  In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol.  (84,  pp. 502-513).  Biomedicine & Pharmacotherapy.

Zhu, Yingdong  Wang, Pei  Sha, Wei  Sang, Shengmin  (2016).  Urinary Biomarkers of Whole Grain Wheat Intake Identified by Non-targeted and Targeted Metabolomics Approaches.  (1,  6,  ).  Scientific Reports.